Bone Graft Substitutes

Orthopedic Devices

Bone Graft Substitutes(25 products)

Bone graft substitutes and materials

A

NMPA Class III, FDA 510(k)

Allgens BonGold Bone Graft Substitute

Allgens Medical (奥精医疗)

Biomimetic mineralized collagen bone graft substitute for orthopedic bone defect repair. Composed of Type I collagen and nano-hydroxyapatite (HA) composite, highly similar to natural bone matrix. China's first and only product with US FDA 510(k) clearance for artificial bone graft.

Biomimetic mineralized collagen technologyType I collagen and nano-HA compositeDegradation rate matches new bone formationFirst Chinese product with US FDA 510(k)

Applications:

Orthopedic bone defect repairTrauma fracture bone lossJoint replacement bone defects

A

NMPA Class III

Allgens ChiBei Bone Graft Substitute

Allgens Medical (奥精医疗)

Biomimetic mineralized collagen bone graft for dental and plastic surgery bone defect repair. Same mineralized collagen technology as BonGold, optimized for maxillofacial applications.

Biomimetic mineralized collagenDental and plastic surgery optimizedExcellent biocompatibilityNatural bone-like composition

Applications:

Dental bone defect repairAlveolar ridge augmentationPlastic surgery bone reconstruction

A

NMPA Class III

Allgens LuRui Bone Graft Substitute

Allgens Medical (奥精医疗)

Biomimetic mineralized collagen bone graft for neurosurgical cranial bone defect repair. Designed for cranioplasty and cranial reconstruction.

Biomimetic mineralized collagenNeurosurgical cranial applicationCranioplasty optimizedNatural bone-like structure

Applications:

Cranial bone defect repairCranioplastyNeurosurgical bone reconstruction

A

NMPA Class III

Allgens Absorbable Composite Bone Graft

Allgens Medical (奥精医疗)

New generation absorbable composite bone repair material. Approved for market in September 2025, featuring enhanced biodegradability and bone regeneration properties.

New generation composite materialEnhanced biodegradabilityImproved bone regenerationApproved September 2025

Applications:

Bone defect repairOrthopedic surgeryTrauma bone reconstruction

R

NMPA Class III

Rebone Calcium Phosphate Cement (CPC)

Rebone Biological Materials (瑞邦生物)

Self-setting calcium phosphate cement bone graft. Non-ceramic hydroxyapatite artificial bone material, developed by华东理工大学教育部医用生物材料工程研究中心. Won Shanghai Science and Technology Special Award. Price is only 20% of imported alternatives.

Self-setting calcium phosphate cementNon-ceramic hydroxyapatiteShanghai Science Special Award winnerPrice 20% of imported alternatives

Applications:

Orthopedic bone defect repairSpinal fusionTrauma bone defects

R

NMPA Class III

Rebone Drug-Loaded Bone Cement

Rebone Biological Materials (瑞邦生物)

Drug-loaded calcium phosphate cement with local drug delivery capability. Used for infected bone defects and bone tumor resection defects with sustained antibiotic release.

Drug-loaded calcium phosphate cementLocal drug delivery capabilitySustained antibiotic releaseInfection prevention

Applications:

Infected bone defectsBone tumor resection defectsAntibiotic-loaded bone repair

R

NMPA Class III

Rebone Injectable Bone Cement

Rebone Biological Materials (瑞邦生物)

Injectable calcium phosphate cement for minimally invasive bone defect repair. Suitable for vertebroplasty and percutaneous bone filling procedures.

Injectable formulationMinimally invasive applicationSelf-setting propertyVertebroplasty compatible

Applications:

VertebroplastyPercutaneous bone defect fillingMinimally invasive bone repair

R

NMPA Class III

Rebone Dental Bone Graft (ChiTai)

Rebone Biological Materials (瑞邦生物)

Dental-specific calcium phosphate cement for alveolar bone repair and augmentation. Optimized for dental implant site preparation and periodontal bone defects.

Dental-specific formulationAlveolar bone repairExcellent osseointegrationDental implant site preparation

Applications:

Alveolar ridge augmentationPeriodontal bone defectsDental implant site preparation

R

NMPA Class III

Rebone Alveolar Bone Graft (YaCaoTai)

Rebone Biological Materials (瑞邦生物)

Specialized alveolar bone repair material for dental ridge preservation and augmentation procedures.

Alveolar ridge preservationDental specialized formulationNatural bone integrationStable volume maintenance

Applications:

Alveolar ridge preservationPost-extraction socket managementDental implant site preparation

J

NMPA Class III

Jiuyuan GUUDOO rhBMP-2 Bone Graft

Jiuyuan Gene (九源基因)

China's first approved rhBMP-2 bone graft substitute. Recombinant human bone morphogenetic protein-2 with pharmaceutical gelatin, soybean lecithin, and hydroxyapatite carrier. Wide approved indications with multiple specifications.

China's first approved rhBMP-2 productRecombinant human BMP-2Gelatin/lecithin/HA carrierWide approved indications

Applications:

Orthopedic bone defect repairSpinal fusionNon-union fracture treatmentBone defect reconstruction

J

NMPA Class III

Jingcheng Magnesium-Containing Bone Graft

Jingcheng Medical (精诚医学)

China's first magnesium-containing degradable polymer bone graft. Uses ultra-low temperature 3D printing to composite magnesium into PLGA and beta-TCP ternary material. For filling and repair of limb bone defects that do not affect bone structural stability.

China's first magnesium-containing bone graftUltra-low temperature 3D printingPLGA/beta-TCP/magnesium ternary compositeBiodegradable polymer

Applications:

Limb bone defect repairNon-load-bearing bone defectsBone defect filling

Z

NMPA Class III (pending)

Zhenghai Ca-Si Bioceramic Bone Graft

Zhenghai Bio (正海生物)

China's first 3D-printed calcium-silicon bioceramic bone graft for jaw bone defect repair. Filed for NMPA registration in November 2024.

First 3D-printed Ca-Si bioceramic in ChinaAdvanced 3D printing technologyCalcium-silicon ceramic compositionJaw bone defect repair

Applications:

Jaw bone defect repairMaxillofacial bone reconstructionDental bone augmentation

M

NMPA Class III

Medprin Bio-Printed Bone Graft

Medprin (迈普医学)

Bioprinted bone graft substitute using advanced 3D bioprinting technology. Specializes in customized craniofacial and maxillofacial bone defect repair with patient-specific designs.

Advanced 3D bioprinting technologyPatient-specific designCraniofacial specializationCustomized bone defect repair

Applications:

Craniofacial reconstructionMaxillofacial bone defectsComplex bone defect repair

G

NMPA Class III

Giant Bio HA Composite Bone Graft

Giant Bio (巨子生物)

Organic-inorganic composite bone graft material. Inorganic component is hydroxyapatite particles consistent with human bone, organic component is macromolecular polysaccharide. Constructs HA particle macro-pores and micro-pores with surface modification for 3D scaffold.

Organic-inorganic compositeHA particles match human bone compositionMacro-pore and micro-pore structure3D scaffold with surface modification

Applications:

Bone defect repairBone regeneration scaffoldOrthopedic surgery

H

NMPA Class III

Huamai ACM Composite Bone Graft

Huamai Medical (华迈医疗)

China's first acellular matrix-based composite artificial bone. Combines decellularized extracellular matrix with inorganic bone substitute materials for enhanced bone regeneration at tissue-bone interfaces.

First ACM-based composite bone in ChinaDecellularized extracellular matrixEnhanced bone regenerationSoft tissue-bone interface repair

Applications:

Bone defect repairSoft tissue-bone interface repairComplex bone defects

B

NMPA Class III

Baiao Xenogeneic HA Composite Bone Fill

Baiao Regenerative (佰傲再生)

China's first xenogeneic bovine-derived bone fill material composite with hyaluronic acid. Combines natural bone matrix with hyaluronic acid for enhanced biocompatibility and bone regeneration.

First xenogeneic HA composite in ChinaBovine-derived natural bone matrixHyaluronic acid compositeEnhanced biocompatibility

Applications:

Bone defect fillingBone regenerationOrthopedic and dental applications

L

NMPA Class III

Lixin Shapeable Absorbable Bone Graft

Lixin Science (立心科学)

Shapable absorbable bone graft material (absorbable regenerated bone). Moldable properties for customized bone defect repair with complete absorption and natural bone replacement over time.

Shapable and moldableFully absorbableNatural bone replacementCustomized defect repair

Applications:

Bone defect repairContour reconstructionOrthopedic surgery

G

NMPA Class III

Guona Beta-TCP Bone Graft Substitute

Guona Technology (国纳科技)

Biodegradable beta-tricalcium phosphate bone graft substitute. Excellent biocompatibility and osteoconductivity for orthopedic bone defect repair.

Beta-tricalcium phosphate materialBiodegradableExcellent osteoconductivityNatural bone-like composition

Applications:

Orthopedic bone defect repairSpinal fusionTrauma bone defects

Y

NMPA Class III

Yihuajian Bioactive Ceramic Bone Graft

Yihuajian (意华健)

Bioactive ceramic bone graft substitute for orthopedic bone defect repair. Provides excellent osteoconductive properties and biocompatibility.

Bioactive ceramic materialExcellent osteoconductive propertiesBiocompatibleNatural bone-like structure

Applications:

Orthopedic bone defect repairJoint reconstructionTrauma bone defects

N

NMPA Class III

Naton Hydroxyapatite Bone Granules

Naton Medical (纳通科技)

Hydroxyapatite bone graft granules for orthopedic bone defect repair. Provides excellent biocompatibility and osteoconductive scaffold for bone regeneration.

Hydroxyapatite materialGranule form for easy packingExcellent osteoconductionBiocompatible

Applications:

Bone defect fillingSpinal fusionJoint reconstruction

S

NMPA Class III

Saining Composite Bone Graft Material

Saining Bio (赛宁生物)

Composite bone graft material combining multiple biomaterials for enhanced bone regeneration and repair.

Multi-material compositeEnhanced bone regenerationBiocompatible designVersatile applications

Applications:

Bone defect repairOrthopedic surgeryDental bone augmentation

X

NMPA Class III

Xinkangchen Demineralized Bone Matrix

Xinkangchen Medical (鑫康辰医学)

Demineralized bone matrix (DBM) graft material with osteoinductive properties. Derived from human allograft bone with growth factors preserved for enhanced bone healing.

Demineralized bone matrixOsteoinductive propertiesPreserved growth factorsHuman allograft derived

Applications:

Bone defect repairSpinal fusionNon-union fracture treatment

L

NMPA Class III

Lianjie Natural Bone Graft Material

Lianjie Bio (联结生物)

Natural bone graft material derived from animal sources for bone defect repair and regeneration.

Natural animal-derived materialExcellent biocompatibilityOsteoconductive scaffoldNatural bone structure

Applications:

Bone defect repairOrthopedic surgeryDental bone augmentation

T

NMPA Class III

Tianqin Bioactive Glass Bone Graft

Tianqin Medical (武汉天勤)

Bioactive glass bone graft substitute for orthopedic bone defect repair. Provides excellent biocompatibility and bone bonding capability.

Bioactive glass materialExcellent bone bondingBiocompatibleVersatile applications

Applications:

Bone defect repairOrthopedic surgeryTrauma bone defects

A

NMPA Class III

Aorui Natural Bone Graft Material

Aorui Bio (奥瑞生物)

Natural bone graft material for orthopedic bone defect repair. Part of the domestic natural bone repair material market alongside Xinkangchen and Lianjie Bio.

Natural bone materialOsteoconductive propertiesBiocompatibleClinical proven

Applications:

Bone defect repairOrthopedic surgerySpinal fusion

More in this Category

Explore other Orthopedic Devices subcategories

Trauma Fixation Systems

Intramedullary Nails

External Fixators

Joint Replacement Implants

Spinal Implants

Sports Medicine Implants

Orthopedic Filler

Orthopedic Navigation Systems

Orthopedic Surgical Guides

Spinal Cord Stimulators

Arthroscopy Instruments

Orthopedic Power Tools

Orthopedic Accessories

Fracture Braces

Other Categories

Surgical Robotics

General Medical Supplies

Surgical Instruments

Diagnostic Equipment

Patient Monitoring

In Vitro Diagnostics (IVD)

Dental Equipment

Ophthalmic Devices